Carbinoxamine maleate is primarily used as an antihistamine in pharmaceutical formulations. It is effective in relieving symptoms associated with allergies, such as sneezing, runny nose, itchy throat, and watery eyes. Due to its ability to cross the blood-brain barrier, it also exhibits sedative effects, making it useful in nighttime cold and allergy preparations. It is often combined with decongestants, analgesics, or cough suppressants in multi-symptom formulations. Its use is common in both adult and pediatric allergy and upper respiratory tract medications.