AICA-Riboside, 5'-Phosphate is widely used in biochemical research to study cellular energy metabolism and the activation of AMP-activated protein kinase (AMPK). It serves as an intermediate in the biosynthesis of purine nucleotides, making it valuable for investigating nucleotide metabolism pathways. In metabolic studies, it helps elucidate the role of AMPK in regulating energy balance, glucose uptake, and lipid metabolism. Additionally, it is utilized in pharmacological research to explore potential therapeutic applications for metabolic disorders such as diabetes and obesity. Its role in enhancing mitochondrial function and cellular energy production also makes it relevant in studies related to aging and neurodegenerative diseases.