Cefquinome sulfate is a broad-spectrum fourth-generation cephalosporin antibiotic widely used in veterinary medicine to treat bacterial infections in livestock, including cattle, pigs, and sheep. It is particularly effective against respiratory tract infections, acute mastitis, and metritis in cattle, as well as respiratory diseases, foot abscesses, and arthritis in pigs. Administered via injection for rapid absorption and systemic distribution, it helps reduce infection spread in herds, improve animal health, and enhance productivity. Cefquinome sulfate is valued for its activity against both Gram-positive and Gram-negative bacteria, including some resistant strains. Proper dosing and adherence to withdrawal periods are crucial for food safety and to prevent antibiotic resistance development.