N‐Nitrosonortriptyline
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description Product Description
No known legitimate applications exist for N‐Nitrosonortriptyline. It is primarily recognized as a nitrosated derivative formed from the metabolic or environmental transformation of nortriptyline, a tricyclic antidepressant. Nitrosation of secondary amines like nortriptyline can occur under certain conditions, such as in the acidic environment of the stomach or during food processing, leading to the formation of N-nitroso compounds. Many N-nitroso compounds are of concern due to their potential mutagenic and carcinogenic properties. As such, N‐Nitrosonortriptyline is studied mainly in toxicological and pharmaceutical research to assess the risks associated with nitrosamine impurities in drug products, particularly in the context of drug safety and regulatory evaluation. Its presence is typically monitored and controlled to minimize exposure in medicinal formulations.
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