Nimesulide is primarily used as a nonsteroidal anti-inflammatory drug (NSAID) to manage pain and inflammation. It is commonly prescribed for conditions such as osteoarthritis, rheumatoid arthritis, and acute musculoskeletal disorders. Additionally, it is effective in treating post-operative pain, dental pain, and dysmenorrhea (menstrual cramps). Its anti-inflammatory and analgesic properties make it a preferred choice for short-term relief in various inflammatory conditions. However, it should be used cautiously due to potential liver-related side effects.