RU23908 is primarily used in scientific research for its interaction with glucocorticoid receptors. It functions as a potent antagonist, making it valuable in studying hormonal regulation, inflammation pathways, and metabolic responses mediated by corticosteroids. Researchers utilize RU23908 to investigate conditions involving glucocorticoid excess, such as Cushing's syndrome, and to explore potential therapeutic interventions in metabolic disorders, immune modulation, and stress-related physiological responses. Its selectivity and antagonistic properties support its role in probing receptor-specific effects without activating downstream steroid signaling.