5-Iodo-2'-deoxyuridine
10mM in DMSO
Reagent
Code: #199032
CAS Number
54-42-2
science Other reagents with same CAS 54-42-2
blur_circular Chemical Specifications
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Molecular Information
Weight
354.1 g/mol
Formula
C₉H₁₁IN₂O₅
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Registry Numbers
EC Number
200-207-8
MDL Number
MFCD00134656
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Storage & Handling
Storage
-20°C
description Product Description
Used primarily as an antiviral agent, especially against herpes simplex virus (HSV). It functions by interfering with viral DNA replication, acting as a thymidine analog that gets incorporated into viral DNA, leading to faulty replication and inhibition of viral growth. It has also been used in research settings to study DNA synthesis and cell proliferation. In some cases, it has been explored for oncolytic virus therapies, where it enhances the selectivity and effectiveness of viruses engineered to target cancer cells. Its use is limited clinically due to toxicity concerns, but it remains valuable in laboratory research and virology studies.
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