4'-Demethylepipodophyllotoxin
Analytical reference substance, 98%
Reagent
Code: #176420
CAS Number
6559-91-7
science Other reagents with same CAS 6559-91-7
blur_circular Chemical Specifications
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Molecular Information
Weight
400.384 g/mol
Formula
C₂₁H₂₀O₈
thermostat
Physical Properties
Melting Point
246-248°C
Boiling Point
626.5°C
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Storage & Handling
Density
1.446 g/mL
Storage
-20ºC
description Product Description
Used primarily as a key intermediate in the synthesis of chemotherapeutic agents like etoposide and teniposide. These drugs are widely employed in the treatment of various cancers, including testicular cancer, small cell lung cancer, lymphomas, and leukemias. The compound contributes to the inhibition of topoisomerase II, an enzyme involved in DNA replication and repair, leading to cancer cell death. Due to its potent biological activity, it plays a critical role in oncology drug development and is valuable in research for designing new anticancer agents.
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