10-Deacetylbaccatin III (10-DAB)

10mM in DMSO

Reagent Code: #168897
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CAS Number 32981-86-5

science Other reagents with same CAS 32981-86-5

blur_circular Chemical Specifications

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Weight 544.59 g/mol
Formula C₂₉H₃₆O₁₀
badge Registry Numbers
MDL Number MFCD00132913
inventory_2 Storage & Handling
Storage -20°C

description Product Description

Used primarily as a key starting material in the semi-synthesis of anticancer drugs, especially paclitaxel (Taxol) and docetaxel (Taxotere). These drugs stabilize microtubules, inhibiting cell division and inducing apoptosis in cancer cells. 10-DAB is preferred over direct extraction of paclitaxel due to higher availability from renewable sources like yew tree needles. It allows for scalable, cost-effective production of taxane-based chemotherapeutics used in treating breast, ovarian, lung, and other cancers. Its structural complexity makes it ideal for targeted chemical modifications to develop new derivatives with improved solubility, efficacy, or reduced resistance.

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inventory 1ml
10-20 days ฿21,580.00

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10-Deacetylbaccatin III (10-DAB)
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Used primarily as a key starting material in the semi-synthesis of anticancer drugs, especially paclitaxel (Taxol) and docetaxel (Taxotere). These drugs stabilize microtubules, inhibiting cell division and inducing apoptosis in cancer cells. 10-DAB is preferred over direct extraction of paclitaxel due to higher availability from renewable sources like yew tree needles. It allows for scalable, cost-effective production of taxane-based chemotherapeutics used in treating breast, ovarian, lung, and other cancers. Its structural complexity makes it ideal for targeted chemical modifications to develop new derivatives with improved solubility, efficacy, or reduced resistance.
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