Amifostine trihydrate
10mM in Water
Reagent
Code: #134207
CAS Number
112901-68-5
science Other reagents with same CAS 112901-68-5
blur_circular Chemical Specifications
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Molecular Information
Weight
268.27 g/mol
Formula
C₅H₁₅N₂O₃PS·₃H₂O
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Registry Numbers
MDL Number
MFCD00453866
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Storage & Handling
Storage
-20°C
description Product Description
Used primarily as a cytoprotective agent in cancer therapy, it helps reduce toxicity caused by chemotherapy and radiation. It protects normal tissues, especially salivary glands, from damage during treatment without interfering with the therapeutic effects on cancer cells. Commonly administered in patients undergoing radiation for head and neck cancers to prevent xerostomia (dry mouth). Also used with certain chemotherapeutic agents like cisplatin to reduce kidney damage and bone marrow suppression. Its selective protection of healthy cells makes it valuable in improving patient tolerance to aggressive treatments.
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