Trans-Platinum diammine dichloride (trans-Pt(NH₃)₂Cl₂), the trans isomer of cisplatin, is primarily utilized in cancer research as a model compound to study platinum-based anticancer agents. It binds to DNA but forms different adducts compared to the cis isomer, making it less cytotoxic and not used clinically for treatment. Researchers investigate its interactions with biological molecules to understand resistance mechanisms developed against cisplatin and other platinum drugs. It is also employed in biochemical studies and as a tool to develop novel therapies that could overcome such resistances, though it has limited direct therapeutic potential due to its geometric isomerism.