Trandolapril is primarily used in the treatment of high blood pressure (hypertension) to help reduce the risk of strokes, heart attacks, and kidney problems. It works by relaxing blood vessels, allowing blood to flow more smoothly and the heart to pump more efficiently. Additionally, it is prescribed to improve survival rates in patients who have experienced heart failure or a heart attack. Trandolapril is often part of a comprehensive treatment plan that includes lifestyle changes such as diet and exercise. It is typically taken orally, and the dosage is adjusted based on the patient's medical condition and response to treatment. Regular monitoring of kidney function and blood pressure is recommended during therapy.