Spirotetramat is widely used in agriculture as an insecticide to control a variety of sucking pests, including aphids, whiteflies, and scales. It is particularly effective in protecting crops such as fruits, vegetables, field crops, and ornamental plants. The chemical works by inhibiting lipid biosynthesis in pests, disrupting their growth and development. This mechanism differs from common insecticides and is effective against pests resistant to other chemical groups. Its systemic activity allows it to be absorbed by plants and distributed throughout their tissues, providing long-lasting protection and reducing the frequency of applications. Spirotetramat is often applied as a foliar spray or soil treatment and can be used both before and after harvest, making it versatile for different agricultural practices. Its use helps improve crop yield and quality by minimizing pest damage.

However, its use must strictly follow recommendations to prevent impacts on the environment and beneficial insects, such as bees and other natural enemies.