Diphenyl sulfone is widely used as a high-temperature solvent in the production of specialty polymers, particularly polyethersulfone (PES) and polysulfone resins. These polymers are valued for their thermal stability, mechanical strength, and chemical resistance, making them suitable for applications in aerospace, automotive, and medical industries.

In the electronics sector, it serves as a key intermediate in the synthesis of photoactive compounds for photoresists, which are essential in semiconductor manufacturing. Additionally, it is employed as a plasticizer and stabilizer in certain high-performance plastics, enhancing their durability and flexibility.

Diphenyl sulfone also finds use in organic synthesis as a reaction medium for high-temperature reactions, where its stability under extreme conditions is advantageous. Its role in the production of dyes and pigments further extends its industrial relevance, contributing to the vibrant and long-lasting colors in textiles and coatings.