Endosulfan sulfate is primarily used in environmental and agricultural research to study the persistence and impact of pesticide residues. It serves as a reference standard in analytical laboratories for the detection and quantification of endosulfan and its metabolites in soil, water, and food samples. This helps in monitoring environmental contamination and ensuring compliance with safety regulations. Additionally, it is utilized in toxicological studies to assess the long-term effects of pesticide exposure on ecosystems and human health. Its role is critical in developing strategies for remediation and minimizing the ecological footprint of agricultural chemicals.