Penoxsulam is widely used as a selective herbicide in rice cultivation. It effectively controls a broad spectrum of weeds, including sedge and broadleaf species, while being safe for rice crops when applied at recommended rates. Its mode of action involves inhibiting the enzyme acetolactate synthase (ALS), which is essential for amino acid synthesis in plants, leading to the death of susceptible weeds. It is commonly applied in both pre- and post-emergence systems in paddy fields. Due to its low application rate and high efficacy, it is favored in integrated weed management programs. Penoxsulam also shows good soil residual activity, providing extended control of germinating weeds. It is often used in combination with other herbicides to enhance spectrum and manage herbicide-resistant weed populations.