Used as a reference standard in analytical laboratories for the detection and quantification of 4-phenylphenol in environmental, industrial, or biological samples. Commonly employed in quality control and calibration procedures for chromatographic techniques such as HPLC and GC-MS to ensure accurate measurement of trace contaminants or degradation products. Also utilized in research settings to study biphenyl compound behavior, including metabolic pathways and environmental persistence. Its standardized concentration allows for precise spike recovery experiments and method validation.