Used as a selective herbicide to control broadleaf weeds in cereal crops, grasslands, and pastures. It is effective against many common weeds while leaving grass crops unharmed. Applied mainly in agriculture, it is often found in formulations for weed control in wheat, barley, and rye fields. Also used in non-crop areas such as lawns, roadsides, and industrial sites. MCPA works by mimicking plant growth hormones, causing uncontrolled growth and eventual death of susceptible plants. Its systemic action allows it to be absorbed through leaves and roots, making it versatile in application methods.

MCPA is typically used in the form of salts or esters, which enhance its water solubility and absorption into plants. It is specific to broadleaf weeds and does not harm narrowleaf grass crops.

However, care must be taken during application to avoid drift and spread to non-target plants, as it may cause environmental impacts and affect other vegetation.