Used as a reference standard in analytical laboratories for the quantification and detection of imidazole compounds in various samples. Commonly applied in pharmaceutical quality control to ensure accuracy in drug formulations containing imidazole derivatives, such as antifungal agents and histamine analogs. Also utilized in research settings for calibration of HPLC, GC, and spectrophotometric methods. Helps maintain consistency and reliability in biochemical assays and metabolic studies where imidazole rings are present.