Guazatine acetate salt is primarily used as a fungicide in agricultural applications. It is effective in controlling fungal diseases in a variety of crops, particularly in fruit trees, vegetables, and ornamental plants. It works by disrupting the cell membranes of fungal pathogens, leading to their inhibition or death. Due to its systemic and protective properties, it is often applied as a foliar spray or soil drench. It is especially valued in managing root rot and damping-off diseases caused by fungi such as Fusarium, Rhizoctonia, and Pythium species. Its use is common in integrated pest management programs where resistance development is a concern, as it exhibits a mode of action that complements other fungicide classes.