Flonicamid is primarily used as a systemic insecticide in agriculture, especially effective against sap-feeding insects such as aphids, whiteflies, and planthoppers. It is commonly applied to crops like vegetables, fruits, tea, and ornamental plants. Due to its unique mode of action, it serves as an important tool in resistance management programs where other insecticides have become less effective. Flonicamid is often favored for integrated pest management (IPM) because it has low toxicity to beneficial insects such as pollinators and natural predators when used correctly. It can be applied through foliar sprays or soil drenches, providing both quick knockdown and residual control. Its systemic nature allows it to be absorbed and distributed within the plant, offering protection even before pests cause significant damage.