Flufenacet is primarily used as a selective herbicide in agriculture, especially in the cultivation of cereals such as wheat and barley. It controls a broad spectrum of annual grasses and certain broadleaf weeds by inhibiting very long-chain fatty acid (VLCFA) synthesis, which is essential for cell membrane formation in susceptible plants. It is commonly applied as a pre-emergence treatment, meaning it is sprayed before the crop and weeds emerge from the soil. This allows Flufenacet to establish in the soil and target germinating weed seedlings, providing early-season weed control. Due to its soil activity and systemic action, it offers residual control, reducing the need for multiple applications. Flufenacet is often formulated in combination with other herbicides to broaden the spectrum of weed control and improve efficacy. Its selectivity makes it suitable for use in integrated weed management programs, helping to reduce competition from weeds and improve crop yield and quality.