Famoxadone is primarily used as a fungicide in agriculture, especially for controlling fungal diseases in crops such as grapes, potatoes, tomatoes, and leafy vegetables. It is effective against a range of pathogens, including downy mildews and other oomycete species, by inhibiting mitochondrial respiration in the fungal cells. Due to its protective and curative properties, it is often applied as a foliar spray to prevent infection and to manage existing disease outbreaks. Its systemic movement within the plant enhances its effectiveness, providing longer-lasting protection. Famoxadone is sometimes combined with other fungicides to improve performance and reduce the risk of resistance development.