Bixafen is primarily used as a fungicide in agriculture, especially in the control of a wide range of fungal diseases in cereals, soybeans, and other crops. It is effective against key pathogens such as rusts, powdery mildew, and leaf spots due to its mode of action as a succinate dehydrogenase inhibitor (SDHI). This disrupts the energy production in fungal cells, leading to their death.

It is often formulated in combination with other fungicides to enhance disease control and reduce the risk of resistance development. Bixafen provides both protective and curative activity, making it valuable during critical growth stages when disease pressure is high. Its systemic nature allows it to be absorbed by plant tissues and offer longer-lasting protection.

Due to its efficacy and crop safety profile, bixafen is widely used in integrated pest management programs, supporting yield protection and improved crop quality in modern farming systems.