Flumetsulam is a selective herbicide used primarily in agriculture to control broadleaf weeds. It is commonly applied in soybean, corn, and wheat crops, where it effectively manages resistant weed species, including those resistant to other herbicide classes like ALS inhibitors. Its low application rate makes it cost-effective and reduces environmental impact. Flumetsulam works by inhibiting the enzyme acetolactate synthase (ALS), disrupting amino acid synthesis in susceptible plants, leading to growth cessation and death. Due to its soil residual activity, it provides extended weed control, which helps in reducing the need for multiple applications. It is often formulated in combination with other herbicides to broaden the spectrum of weed control and improve crop safety.