Used primarily in veterinary medicine, Amitraz is effective against ticks, mites, and lice in livestock and companion animals. It is commonly formulated in dips, sprays, and pour-on treatments for cattle, sheep, and dogs. In agriculture, it controls mite infestations in fruit trees and crops. Amitraz acts as an alpha-adrenergic agonist, disrupting nervous system function in pests. It is also used in beekeeping to manage Varroa mite infestations. Due to its neurotoxic effects, proper dosage and handling are essential to minimize risks to non-target species and avoid residues in food products.