Bradykinin
10mM in DMSO
Reagent
Code: #142483
CAS Number
58-82-2
blur_circular Chemical Specifications
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Molecular Information
Weight
1060.21 g/mol
Formula
C₅₀H₇₃N₁₅O₁₁
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Storage & Handling
Storage
-20°C
description Product Description
Bradykinin is involved in the regulation of blood pressure and plays a key role in the inflammatory response. It causes blood vessels to dilate, leading to lowered blood pressure and increased vascular permeability, which allows immune cells to reach affected tissues more easily. This makes it important in the body's response to injury and infection.
It is also associated with pain sensation, as it stimulates nerve endings and contributes to the feeling of pain during inflammation. Due to its role in vasodilation and vascular permeability, bradykinin is implicated in conditions such as angioedema, especially in patients taking ACE inhibitors, where its accumulation can lead to swelling of deeper skin layers.
In research, bradykinin is used to study cardiovascular function, inflammation pathways, and vascular biology. It serves as a tool to induce controlled hypotension in experimental settings and to investigate the mechanisms of kinin-kallikrein system activity.
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