2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)tetradecanoic acid
95%
science Other reagents with same CAS 919122-99-9
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description Product Description
This is Fmoc-protected 2-aminotetradecanoic acid (Fmoc-α-aminomyristic acid), a specialized building block for solid-phase peptide synthesis (SPPS). The fluorenylmethoxycarbonyl (Fmoc) group protects the α-amino function of the non-proteinogenic amino acid 2-aminotetradecanoic acid, which features a long C12H25 alkyl side chain. In SPPS, the free carboxylic acid is coupled to the resin-bound peptide chain, and the Fmoc is orthogonally removed with piperidine under mild basic conditions, enabling stepwise assembly without affecting other protecting groups. The hydrophobic tetradecyl chain imparts lipophilicity to peptides, aiding membrane interaction, purification of intermediates, and applications in pharmaceuticals, antimicrobial agents, protein engineering, and biotechnology research.
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