(N-[(9H-Fluoren-9-ylmethoxy)carbonyl]glycylamino)methyl acetate
95%
science Other reagents with same CAS 1599440-06-8
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description Product Description
(N-[(9H-Fluoren-9-ylmethoxy)carbonyl]glycylamino)methyl acetate is a specialty chemical intermediate primarily used in peptide synthesis. It incorporates the fluorenylmethoxycarbonyl (Fmoc) protecting group on the glycine amino moiety to shield the nitrogen during synthesis, preventing unwanted side reactions. This is especially valuable in solid-phase peptide synthesis (SPPS), enabling controlled, stepwise assembly of peptide chains. The acetoxymethyl (-CH2OCOCH3) group acts as a temporary protecting group for the primary alcohol functionality in the N-(hydroxymethyl)glycine amide structure, allowing selective deprotection. The Fmoc group is orthogonally removed under mild basic conditions (e.g., piperidine), preserving the peptide integrity, while the acetate can be cleaved hydrolytically. This reagent supports high-purity peptide production for pharmaceutical research, drug development, and biochemical applications.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Appearance | White Powder |
| Purity (%) | 94.5-100% |
| NMR | Conforms to Structure |
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