(N-[(9H-Fluoren-9-ylmethoxy)carbonyl]glycylamino)methyl acetate

95%

Reagent Code: #38685
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CAS Number 1599440-06-8

science Other reagents with same CAS 1599440-06-8

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 368.38 g/mol
Formula C₂₀H₂₀N₂O₅
inventory_2 Storage & Handling
Storage 2-8°C, dry, sealed

description Product Description

(N-[(9H-Fluoren-9-ylmethoxy)carbonyl]glycylamino)methyl acetate is a specialty chemical intermediate primarily used in peptide synthesis. It incorporates the fluorenylmethoxycarbonyl (Fmoc) protecting group on the glycine amino moiety to shield the nitrogen during synthesis, preventing unwanted side reactions. This is especially valuable in solid-phase peptide synthesis (SPPS), enabling controlled, stepwise assembly of peptide chains. The acetoxymethyl (-CH2OCOCH3) group acts as a temporary protecting group for the primary alcohol functionality in the N-(hydroxymethyl)glycine amide structure, allowing selective deprotection. The Fmoc group is orthogonally removed under mild basic conditions (e.g., piperidine), preserving the peptide integrity, while the acetate can be cleaved hydrolytically. This reagent supports high-purity peptide production for pharmaceutical research, drug development, and biochemical applications.

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Test Parameter Specification
Appearance White Powder
Purity (%) 94.5-100%
NMR Conforms to Structure

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿41,940.00

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(N-[(9H-Fluoren-9-ylmethoxy)carbonyl]glycylamino)methyl acetate
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(N-[(9H-Fluoren-9-ylmethoxy)carbonyl]glycylamino)methyl acetate is a specialty chemical intermediate primarily used in peptide synthesis. It incorporates the fluorenylmethoxycarbonyl (Fmoc) protecting group on the glycine amino moiety to shield the nitrogen during synthesis, preventing unwanted side reactions. This is especially valuable in solid-phase peptide synthesis (SPPS), enabling controlled, stepwise assembly of peptide chains. The acetoxymethyl (-CH2OCOCH3) group acts as a t

(N-[(9H-Fluoren-9-ylmethoxy)carbonyl]glycylamino)methyl acetate is a specialty chemical intermediate primarily used in peptide synthesis. It incorporates the fluorenylmethoxycarbonyl (Fmoc) protecting group on the glycine amino moiety to shield the nitrogen during synthesis, preventing unwanted side reactions. This is especially valuable in solid-phase peptide synthesis (SPPS), enabling controlled, stepwise assembly of peptide chains. The acetoxymethyl (-CH2OCOCH3) group acts as a temporary protecting group for the primary alcohol functionality in the N-(hydroxymethyl)glycine amide structure, allowing selective deprotection. The Fmoc group is orthogonally removed under mild basic conditions (e.g., piperidine), preserving the peptide integrity, while the acetate can be cleaved hydrolytically. This reagent supports high-purity peptide production for pharmaceutical research, drug development, and biochemical applications.

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