(S)-4-Methyl-2-(methyl((2-(trimethylsilyl)ethoxy)carbonyl)amino)pentanoic acid
98%
science Other reagents with same CAS 2411590-92-4
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description Product Description
This compound, (S)-N-[2-(trimethylsilyl)ethoxycarbonyl]-N-methylleucine, is a protected derivative of N-methyl-L-leucine used as a building block in peptide synthesis. The Teoc (2-(trimethylsilyl)ethoxycarbonyl) group protects the nitrogen, providing stability during synthesis and enabling selective deprotection under mild fluoride conditions. Its chiral S configuration allows incorporation of the enantiomerically pure L-amino acid residue, essential for maintaining biological activity in therapeutic peptides. This makes it valuable in solid-phase peptide synthesis for constructing complex, stereochemically defined peptide chains in pharmaceutical and medicinal chemistry research. It is compatible with common coupling reagents and solvents.
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