Z-D-Chg-OH is primarily used in peptide synthesis as a building block for creating custom peptides with specific structural and functional properties. Its unique structure allows for the incorporation of non-natural amino acids into peptide chains, enhancing stability and resistance to enzymatic degradation. This makes it valuable in the development of peptide-based drugs, particularly in areas like antimicrobial agents, enzyme inhibitors, and targeted therapeutics. Additionally, it is utilized in research to study peptide conformation and interactions, aiding in the design of novel biomolecules with tailored biological activities.