(2S,4R)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-4-phenylpyrrolidine-2-carboxylic acid

≥95%

Reagent Code: #36547
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CAS Number 1093651-96-7

science Other reagents with same CAS 1093651-96-7

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 413.47 g/mol
Formula C₂₆H₂₃NO₄
badge Registry Numbers
MDL Number MFCD06656464
inventory_2 Storage & Handling
Storage 2-8°C, dry and sealed

description Product Description

This compound, (2S,4R)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-4-phenylpyrrolidine-2-carboxylic acid, is an Fmoc-protected derivative of trans-4-phenylproline. It serves as a specialized building block in solid-phase peptide synthesis (SPPS), where the fluorenylmethoxycarbonyl (Fmoc) group protects the pyrrolidine nitrogen, preventing side reactions during stepwise peptide assembly on a resin. The Fmoc protection is orthogonally removable under mild basic conditions (e.g., piperidine), preserving the integrity of the growing peptide chain. The chiral (2S,4R) configuration and 4-phenyl substitution enable the synthesis of stereospecific peptides with modified properties, essential for pharmaceutical research, drug development, and studies of protein folding or enzyme inhibition.

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Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿15,498.00
inventory 100mg
10-20 days ฿9,720.00
inventory 1g
10-20 days ฿38,817.00

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(2S,4R)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-4-phenylpyrrolidine-2-carboxylic acid
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This compound, (2S,4R)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-4-phenylpyrrolidine-2-carboxylic acid, is an Fmoc-protected derivative of trans-4-phenylproline. It serves as a specialized building block in solid-phase peptide synthesis (SPPS), where the fluorenylmethoxycarbonyl (Fmoc) group protects the pyrrolidine nitrogen, preventing side reactions during stepwise peptide assembly on a resin. The Fmoc protection is orthogonally removable under mild basic conditions (e.g., piperidine), preserving the inte

This compound, (2S,4R)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-4-phenylpyrrolidine-2-carboxylic acid, is an Fmoc-protected derivative of trans-4-phenylproline. It serves as a specialized building block in solid-phase peptide synthesis (SPPS), where the fluorenylmethoxycarbonyl (Fmoc) group protects the pyrrolidine nitrogen, preventing side reactions during stepwise peptide assembly on a resin. The Fmoc protection is orthogonally removable under mild basic conditions (e.g., piperidine), preserving the integrity of the growing peptide chain. The chiral (2S,4R) configuration and 4-phenyl substitution enable the synthesis of stereospecific peptides with modified properties, essential for pharmaceutical research, drug development, and studies of protein folding or enzyme inhibition.

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