Used as a highly effective activating agent in peptide synthesis, facilitating the formation of amide bonds by converting carboxylic acids into active esters. It is particularly valued in solid-phase peptide synthesis due to its stability and low tendency to cause racemization. Also employed in the preparation of sulfonated polymers and as a reagent in organic synthesis for introducing sulfonyl functional groups. Its role as a catalyst or intermediate extends to pharmaceutical manufacturing and the development of specialty chemicals.