Widely used in peptide synthesis, it acts as an additive to suppress racemization during coupling reactions. It enhances the efficiency of carbodiimide-based coupling reagents like EDC, making amide bond formation more effective. Commonly applied in pharmaceutical research and development for synthesizing bioactive peptides and proteins. Also utilized in bioconjugation processes, such as attaching labels or functional groups to biomolecules. Its presence improves yield and purity in solid-phase and solution-phase synthesis. Frequently employed in the preparation of peptide-based drugs and diagnostic agents.