Widely used as a peptide coupling reagent additive, it enhances coupling efficiency and reduces racemization during amide bond formation. It is particularly effective in solid-phase peptide synthesis, where it improves yield and purity. The compound is also employed in the preparation of pharmaceuticals and bioactive molecules requiring high stereochemical integrity. Its trifluoromethyl group contributes to improved solubility and stability in organic solvents, making it suitable for automated synthesis protocols. Additionally, it serves as a corrosion inhibitor in some industrial formulations and has been explored as a building block in agrochemical and medicinal chemistry due to its benzotriazole core and fluorinated substituent.