Widely used in peptide synthesis as a coupling reagent, this compound efficiently promotes the formation of amide bonds between amino acids. It is particularly valued in solid-phase peptide synthesis due to its high reactivity and low racemization, helping preserve stereochemical integrity. The reagent enhances coupling speed and yield, especially with sterically hindered or unreactive amino acids. It is also employed in the synthesis of small molecule pharmaceuticals and complex organic compounds where reliable and fast amide bond formation is critical. Its stability and solubility in common organic solvents make it suitable for automated synthesis platforms.