1-Hydroxy-7-azabenzotriazole is widely used in peptide synthesis as an additive to enhance coupling efficiency. It acts as a catalyst, reducing racemization and improving the yield of peptide bonds during the formation process. This compound is particularly valuable in solid-phase peptide synthesis, where it helps to minimize side reactions and ensures the production of high-purity peptides. Additionally, it is employed in organic synthesis for activating carboxylic acids, making it a versatile reagent in the preparation of amides and esters. Its role in facilitating efficient and selective chemical transformations makes it an essential tool in both academic research and industrial applications.