Methoxypolyethylene glycol is widely used in the pharmaceutical industry as a polymer for drug delivery systems. It enhances the solubility, stability, and bioavailability of poorly soluble drugs, making it a key component in the formulation of injectable and oral medications. Its ability to reduce immunogenicity and prolong circulation time in the body makes it valuable for creating PEGylated proteins and peptides, which are used in treatments for conditions like cancer and chronic diseases.

In the field of biotechnology, it is employed to modify surfaces of nanoparticles and liposomes, improving their biocompatibility and targeting efficiency. This is particularly useful in developing advanced drug delivery systems and diagnostic tools.

Additionally, it serves as a lubricant and coating agent in medical devices, such as catheters and stents, to reduce friction and prevent adverse reactions. In cosmetics, it acts as a moisturizer and emulsifier, enhancing the texture and stability of skincare products. Its versatility and safety profile make it a crucial ingredient across various industries.