BX-912 is primarily used in biochemical research as a potent and selective inhibitor of PDK1 (3-phosphoinositide-dependent protein kinase-1). It is widely applied in studies aimed at understanding the role of PDK1 in cellular signaling pathways, particularly those related to cell growth, survival, and metabolism. Researchers utilize BX-912 to investigate its effects on cancer cells, as PDK1 is often implicated in the progression of various cancers. By inhibiting PDK1, BX-912 helps in elucidating the mechanisms of tumor development and exploring potential therapeutic strategies. Additionally, it is used in studies focused on metabolic disorders and insulin signaling, providing insights into the regulation of glucose homeostasis and energy balance. Its application extends to the development of targeted therapies for diseases where PDK1 activity is dysregulated.