MK-4827 (Niraparib)
10mM in DMSO
Reagent
Code: #204527
CAS Number
1038915-60-4
blur_circular Chemical Specifications
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Molecular Information
Weight
320.39 g/mol
Formula
C₁₉H₂₀N₄O
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Storage & Handling
Storage
-20°C
description Product Description
Used primarily in the treatment of ovarian, fallopian tube, and peritoneal cancers, especially in patients who have recurrent disease and are in complete or partial response to platinum-based chemotherapy. It is also approved for use in certain patients with breast cancer who have inherited BRCA mutations. As a PARP inhibitor, it works by blocking enzymes involved in DNA repair, leading to cancer cell death. The drug is taken orally and allows for targeted therapy with improved progression-free survival in clinical settings.
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