AZD2461

10mM in DMSO

Reagent Code: #134114
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CAS Number 1174043-16-3

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 395.43 g/mol
Formula C₂₂H₂₂FN₃O₃
badge Registry Numbers
MDL Number MFCD24386811
inventory_2 Storage & Handling
Storage -20°C

description Product Description

Used in oncology research as a potent inhibitor of poly(ADP-ribose) polymerase (PARP), particularly targeting tumors with defects in DNA repair pathways. Shows potential in overcoming resistance to earlier PARP inhibitors, making it valuable in studies involving BRCA-mutated and other homologous recombination-deficient cancers. Investigated for its ability to enhance the effects of DNA-damaging agents like chemotherapy and radiation in preclinical models. Currently limited to experimental use and not approved for clinical treatment.

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Size Availability Unit Price Quantity
inventory 1ml
10-20 days ฿5,160.00

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