Used as a highly active palladium-based catalyst in cross-coupling reactions, particularly in Suzuki-Miyaura couplings. It enables efficient carbon-carbon bond formation under mild conditions, often with low catalyst loading. Effective for coupling aryl chlorides, which are less reactive and more cost-effective than bromides or iodides, making it valuable in pharmaceutical and agrochemical synthesis. Tolerant of a wide range of functional groups, allowing use in complex molecule assembly. Commonly applied in late-stage functionalization where high selectivity and minimal side reactions are critical.