Widely used as a highly active catalyst in cross-coupling reactions, particularly in Suzuki-Miyaura coupling, enabling the formation of carbon-carbon bonds between aryl halides and boronic acids. Its electron-rich tricyclohexylphosphine ligand enhances reactivity, especially with sterically hindered substrates. The presence of the 2'-amino group on the biphenyl moiety stabilizes the palladium center and facilitates catalyst turnover, making it effective under mild reaction conditions. Commonly applied in the synthesis of pharmaceuticals, agrochemicals, and complex organic molecules where high selectivity and yield are required. Often preferred in industrial processes due to its robustness and reduced catalyst loading needs.