Widely used as a highly active catalyst in cross-coupling reactions, particularly in Suzuki-Miyaura and Heck reactions, enabling efficient carbon-carbon bond formation. Its robust structure enhances stability and turnover, making it suitable for coupling aryl chlorides, which are less reactive and more cost-effective substrates. Commonly applied in pharmaceutical synthesis and fine chemical manufacturing where high catalytic efficiency and functional group tolerance are required. Performs well under mild conditions and often allows for low catalyst loadings, reducing metal contamination in final products.