Used as a highly active catalyst in cross-coupling reactions, particularly in Suzuki-Miyaura and Buchwald-Hartwig aminations. Its sterically hindered phosphine ligand enhances stability and promotes efficient catalytic turnover under mild conditions. Ideal for forming carbon-carbon and carbon-nitrogen bonds in complex organic synthesis, including pharmaceuticals and agrochemicals. Shows excellent functional group tolerance and high selectivity, even with challenging substrates like aryl chlorides. Commonly employed in industrial-scale processes due to its robustness and reliability.