Widely used as a precatalyst in cross-coupling reactions, especially in Suzuki-Miyaura and Buchwald-Hartwig aminations. Its steric bulk and electron-rich nature enhance catalytic activity and stability, enabling efficient carbon-carbon and carbon-heteroatom bond formation. Commonly applied in pharmaceutical synthesis and fine chemical manufacturing where high selectivity and functional group tolerance are required. Soluble in common organic solvents, making it suitable for homogeneous catalysis under mild reaction conditions.