Used as a palladium-based catalyst in cross-coupling reactions, particularly in Buchwald–Hartwig amination and Suzuki–Miyaura coupling. It enables efficient carbon–nitrogen and carbon–carbon bond formation, which is critical in synthesizing pharmaceuticals, agrochemicals, and functional materials. The sulfonate and amine groups enhance solubility and stability, improving catalytic activity under mild conditions. Often employed in late-stage functionalization due to its tolerance of various functional groups.