Used as a derivatization reagent in analytical chemistry, particularly in gas chromatography-mass spectrometry (GC-MS) for the detection of carbonyl compounds such as aldehydes and ketones. It reacts selectively with carbonyl groups to form stable imine derivatives, enhancing volatility and thermal stability for improved chromatographic performance. Its pentafluorobenzyl group provides strong electron-capturing properties, making it especially useful in electron capture detection (ECD) and negative ion chemical ionization mass spectrometry (NICI-MS), allowing highly sensitive detection of trace-level analytes in environmental and biological samples.