(±)14-HDHA is primarily used in research focused on understanding inflammation and its resolution. It plays a role in studying the mechanisms of bioactive lipid mediators, particularly in the context of resolving inflammatory responses. This compound is also explored for its potential therapeutic applications in conditions like chronic inflammation, autoimmune diseases, and metabolic disorders. Additionally, it is utilized in the development of novel anti-inflammatory drugs and as a tool in biochemical studies to investigate pathways related to lipid signaling and cellular homeostasis.