Guanidinosuccinic acid is primarily studied in the context of biomedical research due to its role as a uremic toxin. It accumulates in patients with chronic kidney disease (CKD) and is associated with various complications, such as oxidative stress, endothelial dysfunction, and cardiovascular issues. Researchers investigate its impact on cellular mechanisms and its potential as a biomarker for assessing kidney function and disease progression. Additionally, it is explored for its effects on metabolic pathways and its contribution to the toxicity observed in uremia. Understanding its behavior helps in developing therapeutic strategies to mitigate its harmful effects in CKD patients.